Overview of research and development

JCMED adheres to the guidance of original innovation and clinical actual needs. There are two major technology platforms has cooperated to established:Shenzhen Engineering Laboratory for Medical Bioactive Materials and Guangdong Engineering Technology Research Center for Medical Bioactive Materials. It is novel in China that the low-temperature rapid prototyping manufacturing technology is used to realize the processing of magnesium-containing biodegradable polymer bone repair materials, so that it can be successfully transformed from laboratory to clinical application. Through the independently developed process technology platform and freeze-drying combination with independent intellectual property rights to provides effective support for the expansion of the company in neurosurgery, orthopedics, stomatology and other surgical implantation fields.

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Beijing Jishuitan Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Shanghai Sixth People's Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Xingtai Orthopaedic Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Xi 'an Honghui Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Shenzhen Second People's Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Peking University Shenzhen Hospital

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Clinical trial launch of a magnesium - containing degradable polymer bone repair material
Guangzhou First People's Hospital
R&D projects

Key R&D plan
Key R&D plan of Guangdong Province, research and industrial development of manufacturing technology and equipment for bioactive bone repair materials

Major special projects
Shenzhen strategic emerging industry development major project, research and development of industrialization of personalized hard tissue defect filling and repair implant product

Entrepreneurial funding projects
Entrepreneurial support project, innovative composite bioactive bone repair scaffold

Special projects
"Innovation chain+industrial chain" integration special project, research and development of industrialization of hard tissue medical additive manufacturing technology and equipment
Authorized patent
Invention patent: bone repair material and preparation method;
Patent number: 201110216591.2
Invention patent: sodium fluoride anti-caries coating agent and preparation method thereof;
Patent number: 201710912119.X
Invention patent: porous bone scaffold and preparation method thereof;
Patent number: 201220402014.2
Invention patents: 3D printing method;
Patent number: 201510604994.2
Invention patent: 3D printing nozzle and intelligent control of 3D printing nozzle;
Patent number: 201611242052.5
Invention patents: 3D printing equipment and material supply mixing system based on 3D printing;
Patent number: 201621471167.7
Utility model: intelligent control 3D printing nozzle device;
Patent number: 201220402014.2
Utility model: 3D printing equipment and material supply mixing system based on 3D printing;
Patent number: 201520734358.7
Utility model: porous bone scaffold;
Patent number: 201220402014.2
Utility model: a 3D printing device for preparing heterogeneous bone repair scaffolds;
Patent number: 201820828310.6

Academic achievements

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
Yifeng Zhang, Jiankun Xu, Ye Chun Ruan,Yufeng Zheng & Ling Qin*
- 《Nature Medicine》
- 2016

Osteogenic magnesium incorporated into PLGA/TCP porous scaffold by 3D printing for repairing challenging bone defect
Yuxiao Lai*, Ye Li, Huijuan Cao, Jing Long, Xinluan Wang*, Long Li, Cairong Lia,Qingyun Jia, Bin Teng, Tingting Tang, Jiang Peng, David Eglin, Mauro Alinif, Dirk W. Grijpma, Geoff Richards, Ling Qin*
- 《Biomaterials》
- 2019

Bacterial inhibition potential of 3D rapid-prototyped magnesium-based porous composite scaffolds–an in vitro efficacy study
Rui Ma*, Yuxiao Lai*, Long Li, Hong-lue Tan, Jia-li Wang, Ye Li, Ting-ting Tang*, Ling Qin*
- 《Scientific Reports》
- 2015